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Cripto is essential to capture mouse epiblast stem cell and human embryonic stem cell pluripotency
Known molecular determinants of developmental plasticity are mainly transcription factors, while the extrinsic regulation of this process has been largely unexplored. Here we identify Cripto as one of the earliest epiblast markers and a key extracellular determinant of the naive and primed pluripote...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5025790/ https://www.ncbi.nlm.nih.gov/pubmed/27586544 http://dx.doi.org/10.1038/ncomms12589 |