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ORP4L is essential for T-cell acute lymphoblastic leukemia cell survival

Metabolic pathways are reprogrammed in cancer to support cell survival. Here, we report that T-cell acute lymphoblastic leukemia (T-ALL) cells are characterized by increased oxidative phosphorylation and robust ATP production. We demonstrate that ORP4L is expressed in T-ALL but not normal T-cells an...

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Detalles Bibliográficos
Autores principales:	Zhong, Wenbin, Yi, Qing, Xu, Bing, Li, Shiqian, Wang, Tong, Liu, Fupei, Zhu, Biying, Hoffmann, Peter R., Ji, Guangju, Lei, Pingsheng, Li, Guoping, Li, Jiwei, Li, Jian, Olkkonen, Vesa M., Yan, Daoguang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5025801/ https://www.ncbi.nlm.nih.gov/pubmed/27581363 http://dx.doi.org/10.1038/ncomms12702

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