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Topical Simvastatin as Host-Directed Therapy against Severity of Cutaneous Leishmaniasis in Mice

We recently demonstrated that statins mediate protection against intracellular pathogens, Mycobacterium tuberculosis and Listeria monocytogenes in mice. Here, we investigated the immunomodulatory potential of simvastatin as a topical or systemic host-directed drug therapy in controlling inflammatory...

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Detalles Bibliográficos
Autores principales:	Parihar, Suraj P., Hartley, Mary-Anne, Hurdayal, Ramona, Guler, Reto, Brombacher, Frank
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5025842/ https://www.ncbi.nlm.nih.gov/pubmed/27632901 http://dx.doi.org/10.1038/srep33458

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