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Multiple novel gene-by-environment interactions modify the effect of FTO variants on body mass index

Genetic studies have shown that obesity risk is heritable and that, of the many common variants now associated with body mass index, those in an intron of the fat mass and obesity-associated (FTO) gene have the largest effect. The size of the UK Biobank, and its joint measurement of genetic, anthrop...

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Detalles Bibliográficos
Autores principales: Young, Alexander I., Wauthier, Fabian, Donnelly, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5025863/
https://www.ncbi.nlm.nih.gov/pubmed/27596730
http://dx.doi.org/10.1038/ncomms12724