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LECT2 drives haematopoietic stem cell expansion and mobilization via regulating the macrophages and osteolineage cells

Haematopoietic stem cells (HSCs) can differentiate into cells of all lineages in the blood. However, the mechanisms by which cytokines in the blood affect HSC homeostasis remain largely unknown. Here we show that leukocyte cell-derived chemotaxin 2 (LECT2), a multifunctional cytokine, induces HSC ex...

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Detalles Bibliográficos
Autores principales:	Lu, Xin-Jiang, Chen, Qiang, Rong, Ye-Jing, Yang, Guan-Jun, Li, Chang-Hong, Xu, Ning-Yi, Yu, Chao-Hui, Wang, Hui-Ying, Zhang, Shun, Shi, Yu-Hong, Chen, Jiong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5025878/ https://www.ncbi.nlm.nih.gov/pubmed/27596364 http://dx.doi.org/10.1038/ncomms12719

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