Cargando…

Endoplasmic Reticulum Stress Links Oxidative Stress to Impaired Pancreatic Beta-Cell Function Caused by Human Oxidized LDL

Elevated plasma concentration of the pro-atherogenic oxidized low density lipoprotein cholesterol (LDL) triggers adverse effects in pancreatic beta-cells and is associated with type 2 diabetes. Here, we investigated whether the endoplasmic reticulum (ER) stress is a key player coupling oxidative str...

Descripción completa

Detalles Bibliográficos
Autores principales:	Plaisance, Valérie, Brajkovic, Saška, Tenenbaum, Mathie, Favre, Dimitri, Ezanno, Hélène, Bonnefond, Amélie, Bonner, Caroline, Gmyr, Valéry, Kerr-Conte, Julie, Gauthier, Benoit R., Widmann, Christian, Waeber, Gérard, Pattou, François, Froguel, Philippe, Abderrahmani, Amar
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5026355/ https://www.ncbi.nlm.nih.gov/pubmed/27636901 http://dx.doi.org/10.1371/journal.pone.0163046

Ejemplares similares

Impaired histone deacetylases 5 and 6 expression mimics the effects of obesity and hypoxia on adipocyte function
por: Bricambert, Julien, et al.
Publicado: (2016)

Islet Brain 1 Protects Insulin Producing Cells against Lipotoxicity
por: Brajkovic, Saška, et al.
Publicado: (2016)

Evidence for tuning adipocytes ICER levels for obesity care
por: Brajkovic, Saška, et al.
Publicado: (2012)

Role for inducible cAMP early repressor in promoting pancreatic beta cell dysfunction evoked by oxidative stress in human and rat islets
por: Favre, D., et al.
Publicado: (2011)

The Class I Histone Deacetylase Inhibitor MS-275 Prevents Pancreatic Beta Cell Death Induced by Palmitate
por: Plaisance, Valérie, et al.
Publicado: (2014)

JNK3 Is Required for the Cytoprotective Effect of Exendin 4
por: Ezanno, Hélène, et al.
Publicado: (2014)

Reduction of Connexin36 Content by ICER-1 Contributes to Insulin-Secreting Cells Apoptosis Induced by Oxidized LDL Particles
por: Haefliger, Jacques-Antoine, et al.
Publicado: (2013)

Role of MicroRNAs in Islet Beta-Cell Compensation and Failure during Diabetes
por: Plaisance, Valérie, et al.
Publicado: (2014)

Differential Trafficking of Oxidized LDL and Oxidized LDL Immune Complexes in Macrophages: Impact on Oxidative Stress
por: Al Gadban, Mohammed M., et al.
Publicado: (2010)

Correction: The GTPase Rab37 Participates in the Control of Insulin Exocytosis
por: Ljubicic, Sanda, et al.
Publicado: (2013)

Oxidized LDL triggers changes in oxidative stress and inflammatory biomarkers in human macrophages
por: Lara-Guzmán, Oscar J., et al.
Publicado: (2017)

Next-generation sequencing for identifying new genes in rare genetic diseases: many challenges and a pinch of luck
por: Bonnefond, Amélie, et al.
Publicado: (2013)

Expression and functional assessment of candidate type 2 diabetes susceptibility genes identify four new genes contributing to human insulin secretion
por: Ndiaye, Fatou K., et al.
Publicado: (2017)

Impaired Expression of the Inducible cAMP Early Repressor Accounts for Sustained Adipose CREB Activity in Obesity
por: Favre, Dimitri, et al.
Publicado: (2011)

Increased Serum ox-LDL Levels Correlated with Lung Function, Inflammation, and Oxidative Stress in COPD
por: Shen, Yongchun, et al.
Publicado: (2013)

Native LDL-induced oxidative stress in human proximal tubular cells: multiple players involved
por: Piccoli, Claudia, et al.
Publicado: (2011)

Acid Sphingomyelinase Mediates Oxidized-LDL Induced Apoptosis in Macrophage via Endoplasmic Reticulum Stress
por: Zhao, Min, et al.
Publicado: (2016)

Baicalein protects against oxLDL-caused oxidative stress and inflammation by modulation of AMPK- alpha
por: Tsai, Kun-Ling, et al.
Publicado: (2016)

Pathological Crosstalk Between Oxidized LDL and ER Stress in Human Diseases: A Comprehensive Review
por: Varghese, Divya Saro, et al.
Publicado: (2021)

Harnessing Oxidative Stress as an Innovative Target for Cancer Therapy
por: Postovit, Lynne, et al.
Publicado: (2018)

Bioactive Compounds of Cooked Tomato Sauce Modulate Oxidative Stress and Arachidonic Acid Cascade Induced by Oxidized LDL in Macrophage Cultures
por: Storniolo, Carolina E., et al.
Publicado: (2019)

Paraoxonase 1: The Lectin-Like Oxidized LDL Receptor Type I and Oxidative Stress in the Blood of Men with Type II Obesity
por: Kupczyk, D., et al.
Publicado: (2019)

Exogenous spermine inhibits high glucose/oxidized LDL-induced oxidative stress and macrophage pyroptosis by activating the Nrf2 pathway
por: Qiu, Yuxuan, et al.
Publicado: (2022)

Triptolide Alleviates Oxidized LDL-Induced Endothelial Inflammation by Attenuating the Oxidative Stress-Mediated Nuclear Factor-Kappa B Pathway
por: Zhang, Shiyu, et al.
Publicado: (2022)

Dual Role of Endothelial Nitric Oxide Synthase in Oxidized LDL-Induced, p66(Shc)-Mediated Oxidative Stress in Cultured Human Endothelial Cells
por: Shi, Yi, et al.
Publicado: (2014)

Traffic Air Pollution and Oxidized LDL
por: Jacobs, Lotte, et al.
Publicado: (2011)

The Dynamics of Oxidized LDL during Atherogenesis
por: Itabe, Hiroyuki, et al.
Publicado: (2011)

Metformin Impedes Oxidation of LDL In Vitro
por: Rossmann, Christine, et al.
Publicado: (2023)

Activation of AMP-Activated Protein Kinase Inhibits Oxidized LDL-Triggered Endoplasmic Reticulum Stress In Vivo
por: Dong, Yunzhou, et al.
Publicado: (2010)

Polymer-Based Nanostructures for Pancreatic Beta-Cell Imaging and Non-Invasive Treatment of Diabetes
por: Behzadifar, Shakila, et al.
Publicado: (2023)

Liraglutide reduces oxidized LDL-induced oxidative stress and fatty degeneration in Raw 264.7 cells involving the AMPK/SREBP1 pathway
por: Wang, Yan-Gui, et al.
Publicado: (2015)

Astragaloside IV Protects Against Oxidized Low-Density Lipoprotein (ox-LDL)-Induced Endothelial Cell Injury by Reducing Oxidative Stress and Inflammation
por: Zhu, Zhongsheng, et al.
Publicado: (2019)

Liraglutide ameliorates oxidized LDL-induced endothelial dysfunction by GLP-1R-dependent downregulation of LOX-1-mediated oxidative stress and inflammation
por: Ying, Wu, et al.
Publicado: (2023)

Effect of irreversibly glycated LDL in human vascular smooth muscle cells: lipid loading, oxidative and inflammatory stress
por: Sima, Anca V, et al.
Publicado: (2010)

mTOR-Dependent Oxidative Stress Regulates oxLDL-Induced Trained Innate Immunity in Human Monocytes
por: Sohrabi, Yahya, et al.
Publicado: (2019)

Berberis microphylla G. Forst (Calafate) Berry Extract Reduces Oxidative Stress and Lipid Peroxidation of Human LDL
por: Olivares-Caro, Lia, et al.
Publicado: (2020)

Oxidized LDL and LOX-1 in Experimental Sepsis
por: Al-Banna, Nadia, et al.
Publicado: (2013)

Oxidized LDL in Inflammation: From Bench to Bedside
por: Tekin, Ishak Ozel, et al.
Publicado: (2013)

Coxsackievirus-B4 Infection of Human Primary Pancreatic Ductal Cell Cultures Results in Impairment of Differentiation into Insulin-Producing Cells
por: Bertin, Antoine, et al.
Publicado: (2019)

6-Shogaol Protects against Oxidized LDL-Induced Endothelial Injruries by Inhibiting Oxidized LDL-Evoked LOX-1 Signaling
por: Wang, Yun kai, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_pe7o3dmvsgcsvdr73qhl4jf851