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Sam68 Is Required for DNA Damage Responses via Regulating Poly(ADP-ribosyl)ation
The rapid and robust synthesis of polymers of adenosine diphosphate (ADP)-ribose (PAR) chains, primarily catalyzed by poly(ADP-ribose) polymerase 1 (PARP1), is crucial for cellular responses to DNA damage. However, the precise mechanisms through which PARP1 is activated and PAR is robustly synthesiz...
Autores principales: | Sun, Xin, Fu, Kai, Hodgson, Andrea, Wier, Eric M., Wen, Matthew G., Kamenyeva, Olena, Xia, Xue, Koo, Lily Y., Wan, Fengyi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5026359/ https://www.ncbi.nlm.nih.gov/pubmed/27635653 http://dx.doi.org/10.1371/journal.pbio.1002543 |
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