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How to Distinguish Conformational Selection and Induced Fit Based on Chemical Relaxation Rates

Protein binding often involves conformational changes. Important questions are whether a conformational change occurs prior to a binding event (‘conformational selection’) or after a binding event (‘induced fit’), and how conformational transition rates can be obtained from experiments. In this arti...

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Detalles Bibliográficos
Autores principales: Paul, Fabian, Weikl, Thomas R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5026370/
https://www.ncbi.nlm.nih.gov/pubmed/27636092
http://dx.doi.org/10.1371/journal.pcbi.1005067

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