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How to Distinguish Conformational Selection and Induced Fit Based on Chemical Relaxation Rates
Protein binding often involves conformational changes. Important questions are whether a conformational change occurs prior to a binding event (‘conformational selection’) or after a binding event (‘induced fit’), and how conformational transition rates can be obtained from experiments. In this arti...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5026370/ https://www.ncbi.nlm.nih.gov/pubmed/27636092 http://dx.doi.org/10.1371/journal.pcbi.1005067 |