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Cathepsin K Deficiency Prevents the Aggravated Vascular Remodeling Response to Flow Cessation in ApoE(-/-) Mice

Cathepsin K (catK) is a potent lysosomal cysteine protease involved in extracellular matrix (ECM) degradation and inflammatory remodeling responses. Here we have investigated the contribution of catK deficiency on carotid arterial remodeling in response to flow cessation in apoE(-/-) and wild type (...

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Detalles Bibliográficos
Autores principales:	Donners, Marjo M. P. C., Bai, Lili, Lutgens, Suzanne P. M., Wijnands, Erwin, Johnson, Jason, Schurgers, Leon J., Liu, Cong-Lin, Daemen, Mat J. A. P., Cleutjens, Kitty B. J. M., Shi, Guo-Ping, Biessen, Erik A. L., Heeneman, Sylvia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5026377/ https://www.ncbi.nlm.nih.gov/pubmed/27636705 http://dx.doi.org/10.1371/journal.pone.0162595

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