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Cyclic di-GMP mediates a histidine kinase/phosphatase switch by noncovalent domain cross-linking
Histidine kinases are key components of regulatory networks in bacteria. Although many of these enzymes are bifunctional, mediating both phosphorylation and dephosphorylation of downstream targets, the molecular details of this central regulatory switch are unclear. We showed recently that the unive...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5026420/ https://www.ncbi.nlm.nih.gov/pubmed/27652341 http://dx.doi.org/10.1126/sciadv.1600823 |