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The selectivity of the Na(+)/K(+)-pump is controlled by binding site protonation and self-correcting occlusion
The Na(+)/K(+)-pump maintains the physiological K(+) and Na(+) electrochemical gradients across the cell membrane. It operates via an 'alternating-access' mechanism, making iterative transitions between inward-facing (E(1)) and outward-facing (E(2)) conformations. Although the general feat...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
eLife Sciences Publications, Ltd
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5026471/ https://www.ncbi.nlm.nih.gov/pubmed/27490484 http://dx.doi.org/10.7554/eLife.16616 |