Signal Integration by the IκB Protein Pickle Shapes Drosophila Innate Host Defense

Pattern recognition receptors are activated following infection and trigger transcriptional programs important for host defense. Tight regulation of NF-κB activation is critical to avoid detrimental and misbalanced responses. We describe Pickle, a Drosophila nuclear IκB that integrates signaling inp...

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Detalles Bibliográficos
Autores principales: Morris, Otto, Liu, Xi, Domingues, Celia, Runchel, Christopher, Chai, Andrea, Basith, Shaherin, Tenev, Tencho, Chen, Haiyang, Choi, Sangdun, Pennetta, Giuseppa, Buchon, Nicolas, Meier, Pascal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5026699/
https://www.ncbi.nlm.nih.gov/pubmed/27631699
http://dx.doi.org/10.1016/j.chom.2016.08.003

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