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Embracing Integrative Multiomics Approaches

As “-omics” data technology advances and becomes more readily accessible to address complex biological questions, increasing amount of cross “-omics” dataset is inspiring the use and development of integrative bioinformatics analysis. In the current review, we discuss multiple options for integratin...

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Detalles Bibliográficos
Autores principales: Rotroff, Daniel M., Motsinger-Reif, Alison A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5027047/
https://www.ncbi.nlm.nih.gov/pubmed/27689071
http://dx.doi.org/10.1155/2016/1715985
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author Rotroff, Daniel M.
Motsinger-Reif, Alison A.
author_facet Rotroff, Daniel M.
Motsinger-Reif, Alison A.
author_sort Rotroff, Daniel M.
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description As “-omics” data technology advances and becomes more readily accessible to address complex biological questions, increasing amount of cross “-omics” dataset is inspiring the use and development of integrative bioinformatics analysis. In the current review, we discuss multiple options for integrating data across “-omes” for a range of study designs. We discuss established methods for such analysis and point the reader to in-depth discussions for the various topics. Additionally, we discuss challenges and new directions in the area.
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spelling pubmed-50270472016-09-29 Embracing Integrative Multiomics Approaches Rotroff, Daniel M. Motsinger-Reif, Alison A. Int J Genomics Review Article As “-omics” data technology advances and becomes more readily accessible to address complex biological questions, increasing amount of cross “-omics” dataset is inspiring the use and development of integrative bioinformatics analysis. In the current review, we discuss multiple options for integrating data across “-omes” for a range of study designs. We discuss established methods for such analysis and point the reader to in-depth discussions for the various topics. Additionally, we discuss challenges and new directions in the area. Hindawi Publishing Corporation 2016 2016-09-04 /pmc/articles/PMC5027047/ /pubmed/27689071 http://dx.doi.org/10.1155/2016/1715985 Text en Copyright © 2016 D. M. Rotroff and A. A. Motsinger-Reif. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Rotroff, Daniel M.
Motsinger-Reif, Alison A.
Embracing Integrative Multiomics Approaches
title Embracing Integrative Multiomics Approaches
title_full Embracing Integrative Multiomics Approaches
title_fullStr Embracing Integrative Multiomics Approaches
title_full_unstemmed Embracing Integrative Multiomics Approaches
title_short Embracing Integrative Multiomics Approaches
title_sort embracing integrative multiomics approaches
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5027047/
https://www.ncbi.nlm.nih.gov/pubmed/27689071
http://dx.doi.org/10.1155/2016/1715985
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