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Computational inference of a genomic pluripotency signature in human and mouse stem cells

Recent analyses of next-generation sequencing datasets have shown that cell-specific regulatory elements in stem cells are marked with distinguishable patterns of transcription factor (TF) binding and epigenetic marks. For example, we recently demonstrated that promoters of cell-specific genes are c...

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Detalles Bibliográficos
Autores principales: Kurum, Esra, Benayoun, Bérénice A., Malhotra, Ankit, George, Joshy, Ucar, Duygu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5027095/
https://www.ncbi.nlm.nih.gov/pubmed/27639379
http://dx.doi.org/10.1186/s13062-016-0148-z