nbCNV: a multi-constrained optimization model for discovering copy number variants in single-cell sequencing data

BACKGROUND: Variations in DNA copy number have an important contribution to the development of several diseases, including autism, schizophrenia and cancer. Single-cell sequencing technology allows the dissection of genomic heterogeneity at the single-cell level, thereby providing important evolutio...

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Detalles Bibliográficos
Autores principales: Zhang, Changsheng, Cai, Hongmin, Huang, Jingying, Song, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5027123/
https://www.ncbi.nlm.nih.gov/pubmed/27639558
http://dx.doi.org/10.1186/s12859-016-1239-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5027123/
https://www.ncbi.nlm.nih.gov/pubmed/27639558
http://dx.doi.org/10.1186/s12859-016-1239-7

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