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Therapeutic Effects of Successful Angioplasty on the Aorta and Lower Limb Arteries on the Healing of Chronic Ischemic Wounds

Background: Chronic wounds are a serious problem for the patient and can increase the socioeconomic burden on the healthcare system and community. This study aimed at investigating the effect of angioplasty on chronic ischemic wound healing. Methods: This study was conducted in Sina Hospital, affili...

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Autores principales: Zafarghandi, Mohammad Reza, Taghavi, Morteza, Farshidmehr, Pezhman, Sayarifard, Azadeh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Tehran University of Medical Sciences, 2006- 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5027165/
https://www.ncbi.nlm.nih.gov/pubmed/27928259
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author Zafarghandi, Mohammad Reza
Taghavi, Morteza
Farshidmehr, Pezhman
Sayarifard, Azadeh
author_facet Zafarghandi, Mohammad Reza
Taghavi, Morteza
Farshidmehr, Pezhman
Sayarifard, Azadeh
author_sort Zafarghandi, Mohammad Reza
collection PubMed
description Background: Chronic wounds are a serious problem for the patient and can increase the socioeconomic burden on the healthcare system and community. This study aimed at investigating the effect of angioplasty on chronic ischemic wound healing. Methods: This study was conducted in Sina Hospital, affiliated to Tehran University of Medical Sciences. Thirty-eight patients with chronic ischemic wounds and a suspicion of the narrowing or blockage of arteries underwent peripheral angiography. Arteries under angioplasty in different patients comprised the aorta and the iliac, superficial femoral, popliteal, and tibial arteries. The patients were evaluated in terms of wound healing in weekly and monthly visits. Wound healing was measured based on the Bates–Jensen criteria. Results: The patients were followed up at a median of 4.5 months. The mean age of the patients was 61.1 ± 7.5 years. Of 38 patients, 12 (31.6%) were female. The involvement of arteries on angiography consisted of 16 (42.2%) cases of total occlusion and 22 (57.8%) cases of stenosis. Following angioplasty, the level of the narrowing of arteries and the wound score showed a significant reduction in all the patients (p value < 0.001). Wound healing was observed in 29 (76.3%) patients. Hematoma, pseudoaneurysm, and thrombosis comprised the complications. No significant differences were observed in terms of age, gender, and history of risk factors between the 2 groups of wound healing and nonhealing. The wound evaluation scores before (p value = 0.044) and after (p value < 0.001) angioplasty were lower in the wound healing group than in the nonhealing group. Conclusion: Angioplasty of the aorta and lower limb arteries improved the healing of chronic ischemic wounds in our patients.
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spelling pubmed-50271652016-12-07 Therapeutic Effects of Successful Angioplasty on the Aorta and Lower Limb Arteries on the Healing of Chronic Ischemic Wounds Zafarghandi, Mohammad Reza Taghavi, Morteza Farshidmehr, Pezhman Sayarifard, Azadeh J Tehran Heart Cent Original Article Background: Chronic wounds are a serious problem for the patient and can increase the socioeconomic burden on the healthcare system and community. This study aimed at investigating the effect of angioplasty on chronic ischemic wound healing. Methods: This study was conducted in Sina Hospital, affiliated to Tehran University of Medical Sciences. Thirty-eight patients with chronic ischemic wounds and a suspicion of the narrowing or blockage of arteries underwent peripheral angiography. Arteries under angioplasty in different patients comprised the aorta and the iliac, superficial femoral, popliteal, and tibial arteries. The patients were evaluated in terms of wound healing in weekly and monthly visits. Wound healing was measured based on the Bates–Jensen criteria. Results: The patients were followed up at a median of 4.5 months. The mean age of the patients was 61.1 ± 7.5 years. Of 38 patients, 12 (31.6%) were female. The involvement of arteries on angiography consisted of 16 (42.2%) cases of total occlusion and 22 (57.8%) cases of stenosis. Following angioplasty, the level of the narrowing of arteries and the wound score showed a significant reduction in all the patients (p value < 0.001). Wound healing was observed in 29 (76.3%) patients. Hematoma, pseudoaneurysm, and thrombosis comprised the complications. No significant differences were observed in terms of age, gender, and history of risk factors between the 2 groups of wound healing and nonhealing. The wound evaluation scores before (p value = 0.044) and after (p value < 0.001) angioplasty were lower in the wound healing group than in the nonhealing group. Conclusion: Angioplasty of the aorta and lower limb arteries improved the healing of chronic ischemic wounds in our patients. Tehran University of Medical Sciences, 2006- 2016-04-13 /pmc/articles/PMC5027165/ /pubmed/27928259 Text en Copyright © 2015 Tehran Heart Center, Tehran University of Medical Sciences This is an Open Access article distributed under the terms of the Creative Commons Attribution License, (http://creativecommons.org/licenses/by/3.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Zafarghandi, Mohammad Reza
Taghavi, Morteza
Farshidmehr, Pezhman
Sayarifard, Azadeh
Therapeutic Effects of Successful Angioplasty on the Aorta and Lower Limb Arteries on the Healing of Chronic Ischemic Wounds
title Therapeutic Effects of Successful Angioplasty on the Aorta and Lower Limb Arteries on the Healing of Chronic Ischemic Wounds
title_full Therapeutic Effects of Successful Angioplasty on the Aorta and Lower Limb Arteries on the Healing of Chronic Ischemic Wounds
title_fullStr Therapeutic Effects of Successful Angioplasty on the Aorta and Lower Limb Arteries on the Healing of Chronic Ischemic Wounds
title_full_unstemmed Therapeutic Effects of Successful Angioplasty on the Aorta and Lower Limb Arteries on the Healing of Chronic Ischemic Wounds
title_short Therapeutic Effects of Successful Angioplasty on the Aorta and Lower Limb Arteries on the Healing of Chronic Ischemic Wounds
title_sort therapeutic effects of successful angioplasty on the aorta and lower limb arteries on the healing of chronic ischemic wounds
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5027165/
https://www.ncbi.nlm.nih.gov/pubmed/27928259
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