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Dexamethasone and Monophosphoryl Lipid A-Modulated Dendritic Cells Promote Antigen-Specific Tolerogenic Properties on Naive and Memory CD4(+) T Cells

Tolerogenic dendritic cells (DCs) are a promising tool to control T cell-mediated autoimmunity. Here, we evaluate the ability of dexamethasone-modulated and monophosphoryl lipid A (MPLA)-activated DCs [MPLA-tolerogenic DCs (tDCs)] to exert immunomodulatory effects on naive and memory CD4(+) T cells...

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Detalles Bibliográficos
Autores principales:	Maggi, Jaxaira, Schinnerling, Katina, Pesce, Bárbara, Hilkens, Catharien M., Catalán, Diego, Aguillón, Juan C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2016
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5027201/ https://www.ncbi.nlm.nih.gov/pubmed/27698654 http://dx.doi.org/10.3389/fimmu.2016.00359

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