Anks1a regulates COPII-mediated anterograde transport of receptor tyrosine kinases critical for tumorigenesis

ErbB2 signalling, which is amplified by EphA2 binding, is an important therapeutic target for breast cancer. Despite the importance of the EphA2/ErbB2 complex in promoting breast tumorigenesis, the mechanism by which these receptor tyrosine kinases (RTKs) are exported from the endoplasmic reticulum...

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Detalles Bibliográficos
Autores principales: Lee, Haeryung, Noh, Hyuna, Mun, Jiyoung, Gu, Changkyu, Sever, Sanja, Park, Soochul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5027278/
https://www.ncbi.nlm.nih.gov/pubmed/27619642
http://dx.doi.org/10.1038/ncomms12799

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5027278/
https://www.ncbi.nlm.nih.gov/pubmed/27619642
http://dx.doi.org/10.1038/ncomms12799

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