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Nox2 contributes to the arterial endothelial specification of mouse induced pluripotent stem cells by upregulating Notch signaling

Reactive oxygen species (ROS) have a crucial role in stem-cell differentiation; however, the mechanisms by which ROS regulate the differentiation of stem cells into endothelial cells (ECs) are unknown. Here, we determine the role of ROS produced by NADPH oxidase 2 (Nox2) in the endothelial-lineage s...

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Detalles Bibliográficos
Autores principales: Kang, Xueling, Wei, Xiangxiang, Wang, Xinhong, Jiang, Li, Niu, Cong, Zhang, Jianyi, Chen, Sifeng, Meng, Dan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5027389/
https://www.ncbi.nlm.nih.gov/pubmed/27642005
http://dx.doi.org/10.1038/srep33737

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