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MutS regulates access of the error-prone DNA polymerase Pol IV to replication sites: a novel mechanism for maintaining replication fidelity

Translesion DNA polymerases (Pol) function in the bypass of template lesions to relieve stalled replication forks but also display potentially deleterious mutagenic phenotypes that contribute to antibiotic resistance in bacteria and lead to human disease. Effective activity of these enzymes requires...

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Detalles Bibliográficos
Autores principales:	Margara, Lucía M., Fernández, Marisa M., Malchiodi, Emilio L., Argaraña, Carlos E., Monti, Mariela R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2016
Materias:	Genome Integrity, Repair and Replication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5027486/ https://www.ncbi.nlm.nih.gov/pubmed/27257069 http://dx.doi.org/10.1093/nar/gkw494

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