Parallel analysis of ribonucleotide-dependent deletions produced by yeast Top1 in vitro and in vivo

Ribonucleotides are the most abundant non-canonical component of yeast genomic DNA and their persistence is associated with a distinctive mutation signature characterized by deletion of a single repeat unit from a short tandem repeat. These deletion events are dependent on DNA topoisomerase I (Top1)...

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Detalles Bibliográficos
Autores principales: Cho, Jang-Eun, Huang, Shar-yin N., Burgers, Peter M., Shuman, Stewart, Pommier, Yves, Jinks-Robertson, Sue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5027487/
https://www.ncbi.nlm.nih.gov/pubmed/27257064
http://dx.doi.org/10.1093/nar/gkw495

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5027487/
https://www.ncbi.nlm.nih.gov/pubmed/27257064
http://dx.doi.org/10.1093/nar/gkw495

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