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Cracking the control of RNA polymerase II elongation by 7SK snRNP and P-TEFb
Release of RNA polymerase II (Pol II) from promoter-proximal pausing has emerged as a critical step regulating gene expression in multicellular organisms. The transition of Pol II into productive elongation requires the kinase activity of positive transcription elongation factor b (P-TEFb), which is...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5027500/ https://www.ncbi.nlm.nih.gov/pubmed/27369380 http://dx.doi.org/10.1093/nar/gkw585 |