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Genome-wide analysis reveals positional-nucleosome-oriented binding pattern of pioneer factor FOXA1

The compaction of nucleosomal structures creates a barrier for DNA-binding transcription factors (TFs) to access their cognate cis-regulatory elements. Pioneer factors (PFs) such as FOXA1 are able to directly access these cis-targets within compact chromatin. However, how these PFs interplay with nu...

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Detalles Bibliográficos
Autores principales:	Ye, Zhenqing, Chen, Zhong, Sunkel, Benjamin, Frietze, Seth, Huang, Tim H.-M., Wang, Qianben, Jin, Victor X.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2016
Materias:	Computational Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5027512/ https://www.ncbi.nlm.nih.gov/pubmed/27458208 http://dx.doi.org/10.1093/nar/gkw659

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