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A contaminant-free assessment of Endogenous Retroviral RNA in human plasma

Endogenous retroviruses (ERVs) comprise 6–8% of the human genome. HERVs are silenced in most normal tissues, up-regulated in stem cells and in placenta but also in cancer and HIV-1 infection. Crucially, there are conflicting reports on detecting HERV RNA in non-cellular clinical samples such as plas...

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Detalles Bibliográficos
Autores principales: Karamitros, Timokratis, Paraskevis, Dimitrios, Hatzakis, Angelos, Psichogiou, Mina, Elefsiniotis, Ioannis, Hurst, Tara, Geretti, Anna-Maria, Beloukas, Apostolos, Frater, John, Klenerman, Paul, Katzourakis, Aris, Magiorkinis, Gkikas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5027517/
https://www.ncbi.nlm.nih.gov/pubmed/27640347
http://dx.doi.org/10.1038/srep33598