Linear biocompatible glyco-polyamidoamines as dual action mode virus infection inhibitors with potential as broad-spectrum microbicides for sexually transmitted diseases

The initial steps of viral infections are mediated by interactions between viral proteins and cellular receptors. Blocking the latter with high-affinity ligands may inhibit infection. DC-SIGN, a C-type lectin receptor expressed by immature dendritic cells and macrophages, mediates human immunodefici...

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Detalles Bibliográficos
Autores principales: Mauro, Nicolò, Ferruti, Paolo, Ranucci, Elisabetta, Manfredi, Amedea, Berzi, Angela, Clerici, Mario, Cagno, Valeria, Lembo, David, Palmioli, Alessandro, Sattin, Sara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5027566/
https://www.ncbi.nlm.nih.gov/pubmed/27641362
http://dx.doi.org/10.1038/srep33393

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