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Potential pitfalls of mass spectrometry to uncover mutations in childhood soft tissue sarcoma: A report from the Children’s Oncology Group

Mass spectrometry-based methods have been widely applied – often as the sole method – to detect mutations in human cancer specimens. We applied this approach to 52 childhood soft tissue sarcoma specimens in an attempt to identify potentially actionable mutations. This analysis revealed that 25% of t...

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Detalles Bibliográficos
Autores principales: Xu, Lin, Wilson, Raphael A., Laetsch, Theodore W., Oliver, Dwight, Spunt, Sheri L., Hawkins, Douglas S., Skapek, Stephen X.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5027578/
https://www.ncbi.nlm.nih.gov/pubmed/27642091
http://dx.doi.org/10.1038/srep33429

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