BMS-708163 and Nilotinib restore synaptic dysfunction in human embryonic stem cell-derived Alzheimer’s disease models

Alzheimer’s disease (AD) is the most common form of dementia. Cellular AD models derived from human pluripotent stem cells are promising tools in AD research. We recently developed human embryonic stem cell-derived AD models which overexpress mutant Presenilin1 genes, and which exhibit AD phenotypes...

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Detalles Bibliográficos
Autores principales: Nishioka, Hisae, Tooi, Norie, Isobe, Takehisa, Nakatsuji, Norio, Aiba, Kazuhiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5027582/
https://www.ncbi.nlm.nih.gov/pubmed/27641902
http://dx.doi.org/10.1038/srep33427

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