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N-Glycosylation of integrin α5 acts as a switch for EGFR-mediated complex formation of integrin α5β1 to α6β4
N-Glycosylation of integrin α5β1 is involved in multiple cell behaviors. We previously reported that the N-glycosylations of the calf domain on integrin α5 (S3–5,10–14) are essential for its inhibitory effect on EGFR signaling in regulating cell proliferation. However, the importance of the individu...
Autores principales: | Hang, Qinglei, Isaji, Tomoya, Hou, Sicong, Zhou, Ying, Fukuda, Tomohiko, Gu, Jianguo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5027594/ https://www.ncbi.nlm.nih.gov/pubmed/27641064 http://dx.doi.org/10.1038/srep33507 |
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