Cargando…

A combination hepatoma-targeted therapy based on nanotechnology: pHRE-Egr1-HSV-TK/(131)I-antiAFPMcAb-GCV/MFH

Combination targeted therapy is a promising cancer therapeutic strategy. Here, using PEI-Mn(0.5)Zn(0.5)Fe(2)O(4) nanoparticles (PEI-MZF-NPs) as magnetic media for MFH (magnetic fluid hyperthermia) and gene transfer vector for gene-therapy, a combined therapy, pHRE-Egr1-HSV-TK/(131)I-antiAFPMcAb-GCV/...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lin, Mei, Huang, Junxing, Jiang, Xingmao, Zhang, Jia, Yu, Hong, Ye, Jun, Zhang, Dongsheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5027595/ https://www.ncbi.nlm.nih.gov/pubmed/27642033 http://dx.doi.org/10.1038/srep33524

Ejemplares similares

The Possible Mechanisms of HSV-TK/Hyperthermia Combined with 131I-antiAFPMcAb-GCV Nanospheres to Treat Hepatoma
por: Lin, Mei, et al.
Publicado: (2018)

Hepatoma-Targeted Radionuclide Immune Albumin Nanospheres: (131)I-antiAFPMcAb-GCV-BSA-NPs
por: Lin, Mei, et al.
Publicado: (2016)

Synergistic effect of resveratrol and HSV-TK/GCV therapy on murine hepatoma cells
por: Xiao, Jianyong, et al.
Publicado: (2018)

Gene Therapy with HSV1-sr39TK/GCV Exhibits a Stronger Therapeutic Efficacy Than HSV1-TK/GCV in Rat C6 Glioma Cells
por: Li, Lei-qing, et al.
Publicado: (2013)

Efficacy of HSV-TK/GCV system suicide gene therapy using SHED expressing modified HSV-TK against lung cancer brain metastases
por: Oishi, Tomoya, et al.
Publicado: (2022)

HSV-tk/GCV gene therapy mediated by EBV-LMP1 for EBV-associated cancer
por: Lifang, Yang, et al.
Publicado: (2008)

CBMS-08 INVESTIGATION FOR NICOTINIC EFFECTS ON STEM CELL’S PROPERTY IN HSV-TK/GCV GENE THERAPY
por: Kenmochi, Hiroaki, et al.
Publicado: (2019)

HSV-TK/GCV can induce cytotoxicity of retinoblastoma cells through autophagy inhibition by activating MAPK/ERK
por: Yi, Quan-Yong, et al.
Publicado: (2018)

An experimental study on cervix cancer with combination of HSV-TK/GCV suicide gene therapy system and (60)Co radiotherapy
por: Chen, Daozhen, et al.
Publicado: (2010)

Combination of PEI-Mn(0.5)Zn(0.5)Fe(2)O(4) nanoparticles and pHsp 70-HSV-TK/GCV with magnet-induced heating for treatment of hepatoma
por: Tang, Qiusha, et al.
Publicado: (2015)

Using HSV-TK/GCV suicide gene therapy to inhibit lens epithelial cell proliferation for treatment of posterior capsular opacification
por: Jiang, Yong-Xiang, et al.
Publicado: (2011)

HSVtk/GCV system on hepatoma carcinoma cells: Construction of the plasmid pcDNA3.1-pAFP-TK and targeted killing effect
por: Li, Yong-Fang, et al.
Publicado: (2017)

Curcumin plays a synergistic role in combination with HSV-TK/GCV in inhibiting growth of murine B16 melanoma cells and melanoma xenografts
por: Li, Hong, et al.
Publicado: (2019)

Long terminal repeats (LTR) and transcription factors regulate PHRE1 and PHRE2 activity in Moso bamboo under heat stress
por: Papolu, Pradeep K., et al.
Publicado: (2021)

β2-Adrenergic receptor agonist enhances the bystander effect of HSV-TK/GCV gene therapy in glioblastoma multiforme via upregulation of connexin 43 expression
por: Hosseindoost, Saereh, et al.
Publicado: (2022)

ARE/SUZ12 dual specifically-regulated adenoviral TK/GCV system for CML blast crisis cells
por: Zu, Bailing, et al.
Publicado: (2015)

Correction to: ARE/SUZ12 dual specifically-regulated adenoviral TK/GCV system for CML blast crisis cells
por: Zu, Bailing, et al.
Publicado: (2022)

Proteomic Analysis of Bladder Cancer Indicates Prx-I as a Key Molecule in BI-TK/GCV Treatment System
por: Jiang, Li, et al.
Publicado: (2014)

Noninvasive Theranostic Imaging of HSV1-sr39TK-NTR/GCV-CB1954 Dual-Prodrug Therapy in Metastatic Lung Lesions of MDA-MB-231 Triple Negative Breast Cancer in Mice
por: Sekar, Thillai V., et al.
Publicado: (2014)

MFH Mimic in Breast: A High-Grade Malignant Phyllodes Tumor
por: Hemalatha, A. L., et al.
Publicado: (2012)

Targeted Inhibitory Effect of Nasopharyngeal Carcinoma Cells by Hre(2).Grp78 Chimeric Promoter Regulating Fusion Gene TK/VP3
por: Li, Jin-Yun, et al.
Publicado: (2019)

Two Alternative Splicing Variants of AtERF73/HRE1, HRE1α and HRE1β, Have Differential Transactivation Activities in Arabidopsis
por: Seok, Hye-Yeon, et al.
Publicado: (2020)

Antagonistic Roles for GcvA and GcvB in hdeAB Expression in Escherichia coli
por: Stauffer, Lorraine T., et al.
Publicado: (2012)

STAT3/NF-κB-Regulated Lentiviral TK/GCV Suicide Gene Therapy for Cisplatin-Resistant Triple-Negative Breast Cancer
por: Kuo, Wei-Ying, et al.
Publicado: (2017)

Corrigendum to “Targeted Inhibitory Effect of Nasopharyngeal: Carcinoma Cells by Hre2.Grp78 Chimeric Promoter Regulating Fusion Gene TK/VP3”
Publicado: (2020)

Permissible Home Range Estimation (PHRE) in Restricted Habitats: A New Algorithm and an Evaluation for Sea Otters
por: Tarjan, L. Max, et al.
Publicado: (2016)

A novel Bifidobacterium infantis-mediated TK/GCV suicide gene therapy system exhibits antitumor activity in a rat model of bladder cancer
por: Tang, Wei, et al.
Publicado: (2009)

Dexamethasone inhibits the HSV-tk/ ganciclovir bystander effect in malignant glioma cells
por: Robe, Pierre A, et al.
Publicado: (2005)

Unrepairable DNA Double Strand Breaks Initiate Cytotoxicity with HSV-TK/Ganciclovir
por: Ladd, Brendon, et al.
Publicado: (2011)

Ring-Opening Polymerization of ε-Caprolactone Initiated by Ganciclovir (GCV) for the Preparation of GCV-Tagged Polymeric Micelles
por: Sawdon, Alicia J., et al.
Publicado: (2015)

Bystander-Mediated Regression of Murine Neuroblastoma via Retroviral Transfer of the HSV-TK Gene
por: Cho, Hyun-Sang, et al.
Publicado: (2004)

Exogenous p53 and ASPP2 expression enhances rAdV-TK/GCV-induced death in hepatocellular carcinoma cells lacking functional p53
por: Liu, Xiuhong, et al.
Publicado: (2016)

Ovarian Cancer Gene Therapy Using HPV-16 Pseudovirion Carrying the HSV-tk Gene
por: Hung, Chien-Fu, et al.
Publicado: (2012)

HSV-TK Expressing Mesenchymal Stem Cells Exert Inhibitory Effect on Cervical Cancer Model
por: Kenarkoohi, Azra, et al.
Publicado: (2020)

Polymeric Nanovectors Incorporated with Ganciclovir and HSV-tk Encoding Plasmid for Gene-Directed Enzyme Prodrug Therapy
por: Sawdon, Alicia J., et al.
Publicado: (2021)

Initial TK-deficient HSV-1 infection in the lip alters contralateral lip challenge immune dynamics
por: Rousseau, Antoine, et al.
Publicado: (2022)

Determination of the small RNA GcvB regulon in the Gram-negative bacterial pathogen Pasteurella multocida and identification of the GcvB seed binding region
por: Gulliver, Emily L., et al.
Publicado: (2018)

The therapeutic effect of PEI-Fe(3)O(4)/pYr-ads-8-5HRE-cfosp-IFNG albumin nanospheres combined with magnetic fluid hyperthermia on hepatoma
por: Zhang, Hao, et al.
Publicado: (2023)

The Roles of Macrophages and Nitric Oxide in Interleukin-3-Enhanced HSV-Sr39tk-Mediated Prodrug Therapy
por: Yu, Ching-Fang, et al.
Publicado: (2013)

Dioscin augments HSV-tk-mediated suicide gene therapy for melanoma by promoting connexin-based intercellular communication
por: Xiao, Jianyong, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_cim434omrs3q21tdfgmf4qbq02