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An experimental phylogeny to benchmark ancestral sequence reconstruction
Ancestral sequence reconstruction (ASR) is a still-burgeoning method that has revealed many key mechanisms of molecular evolution. One criticism of the approach is an inability to validate its algorithms within a biological context as opposed to a computer simulation. Here we build an experimental p...
Autores principales: | Randall, Ryan N., Radford, Caelan E., Roof, Kelsey A., Natarajan, Divya K., Gaucher, Eric A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5027606/ https://www.ncbi.nlm.nih.gov/pubmed/27628687 http://dx.doi.org/10.1038/ncomms12847 |
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