IL-13Rα2 uses TMEM219 in chitinase 3-like-1-induced signalling and effector responses

Recent studies demonstrated that chitinase 3-like-1 (Chi3l1) binds to and signals via IL-13Rα2. However, the mechanism that IL-13Rα2 uses to mediate the effects of Chi3l1 has not been defined. Here, we demonstrate that the membrane protein, TMEM219, is a binding partner of IL-13Rα2 using yeast two-h...

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Detalles Bibliográficos
Autores principales: Lee, Chang-Min, He, Chuan Hua, Nour, Adel M., Zhou, Yang, Ma, Bing, Park, Jin Wook, Kim, Kyung Hee, Cruz, Charles Dela, Sharma, Lokesh, Nasr, Mahmoud L., Modis, Yorgo, Lee, Chun Geun, Elias, Jack A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5027616/
https://www.ncbi.nlm.nih.gov/pubmed/27629921
http://dx.doi.org/10.1038/ncomms12752

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