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Individual and Combined Expression of DNA Damage Response Molecules PARP1, γH2AX, BRCA1, and BRCA2 Predict Shorter Survival of Soft Tissue Sarcoma Patients

DNA damage response (DDR) molecules are protective against genotoxic stresses. DDR molecules are also involved in the survival of cancer cells in patients undergoing anti-cancer therapies. Therefore, DDR molecules are potential markers of cancer progression in addition to being potential therapeutic...

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Detalles Bibliográficos
Autores principales: Kim, Kyoung Min, Moon, Young Jae, Park, See-Hyoung, Park, Hye Jeong, Wang, Sung Il, Park, Ho Sung, Lee, Ho, Kwon, Keun Sang, Moon, Woo Sung, Lee, Dong Geun, Kim, Jung Ryul, Jang, Kyu Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5028069/
https://www.ncbi.nlm.nih.gov/pubmed/27643881
http://dx.doi.org/10.1371/journal.pone.0163193