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Reduced thermal sensitivity and increased opioidergic tone in the TASTPM mouse model of Alzheimer's disease

Individuals with Alzheimer's disease (AD) are in susceptible patient groups in which pain is an important clinical issue that is often underdiagnosed. However, it is unclear whether decreased pain complaints in patients with AD result from elevated pain tolerance or an impaired ability to commu...

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Detalles Bibliográficos
Autores principales: Aman, Yahyah, Pitcher, Thomas, Simeoli, Raffaele, Ballard, Clive, Malcangio, Marzia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5028157/
https://www.ncbi.nlm.nih.gov/pubmed/27306045
http://dx.doi.org/10.1097/j.pain.0000000000000644