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Bone marrow-derived and resident liver macrophages display unique transcriptomic signatures but similar biological functions
BACKGROUND & AIMS: Kupffer cells (KCs), the resident tissue macrophages of the liver, play a crucial role in the clearance of pathogens and other particulate materials that reach the systemic circulation. Recent studies have identified KCs as a yolk sac-derived resident macrophage population tha...
Autores principales: | Beattie, Lynette, Sawtell, Amy, Mann, Jason, Frame, Teija C.M., Teal, Bianca, de Labastida Rivera, Fabian, Brown, Najmeeyah, Walwyn-Brown, Katherine, Moore, John W.J., MacDonald, Sandy, Lim, Eng-Kiat, Dalton, Jane E., Engwerda, Christian R., MacDonald, Kelli P., Kaye, Paul M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5028381/ https://www.ncbi.nlm.nih.gov/pubmed/27262757 http://dx.doi.org/10.1016/j.jhep.2016.05.037 |
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