Cargando…
CDK1 phosphorylates WRN at collapsed replication forks
Regulation of end-processing is critical for accurate repair and to switch between homologous recombination (HR) and non-homologous end joining (NHEJ). End resection is a two-stage process but very little is known about regulation of the long-range resection, especially in humans. WRN participates i...
Autores principales: | Palermo, Valentina, Rinalducci, Sara, Sanchez, Massimo, Grillini, Francesca, Sommers, Joshua A., Brosh, Robert M., Zolla, Lello, Franchitto, Annapaola, Pichierri, Pietro |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5028418/ https://www.ncbi.nlm.nih.gov/pubmed/27634057 http://dx.doi.org/10.1038/ncomms12880 |
Ejemplares similares
-
PHOSPHORYLATION-DEPENDENT ASSOCIATION OF WRN WITH RPA IS REQUIRED FOR RECOVERY OF REPLICATION FORKS STALLED AT SECONDARY DNA STRUCTURES
por: Noto, Alessandro, et al.
Publicado: (2023) -
Replication fork stalling in WRN-deficient cells is overcome by prompt activation of a MUS81-dependent pathway
por: Franchitto, Annapaola, et al.
Publicado: (2008) -
THE RAD9-RAD1-HUS1 (9.1.1) COMPLEX INTERACTS WITH WRN AND IS CRUCIAL TO REGULATE ITS RESPONSE TO REPLICATION FORK STALLING
por: Pichierri, Pietro, et al.
Publicado: (2011) -
Phosphorylation by CK2 regulates MUS81/EME1 in mitosis and after replication stress
por: Palma, Anita, et al.
Publicado: (2018) -
The WRN exonuclease domain protects nascent strands from pathological MRE11/EXO1-dependent degradation
por: Iannascoli, Chiara, et al.
Publicado: (2015)