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Craniopharyngiomas : Radiological Differentiation of Two Types
OBJECTIVE: To determine imaging features that may separate adamantinomatous and papillary variants of craniopharyngiomas given that tumors with adamantinomatous signature features are associated with higher recurrence rates, morbidity, and mortality. We specifically reviewed calcification on CT, T1...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Korean Neurosurgical Society
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5028606/ https://www.ncbi.nlm.nih.gov/pubmed/27651864 http://dx.doi.org/10.3340/jkns.2016.59.5.466 |
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author | Lee, In Ho Zan, Elcin Bell, W. Robert Burger, Peter C. Sung, Heejong Yousem, David M. |
author_facet | Lee, In Ho Zan, Elcin Bell, W. Robert Burger, Peter C. Sung, Heejong Yousem, David M. |
author_sort | Lee, In Ho |
collection | PubMed |
description | OBJECTIVE: To determine imaging features that may separate adamantinomatous and papillary variants of craniopharyngiomas given that tumors with adamantinomatous signature features are associated with higher recurrence rates, morbidity, and mortality. We specifically reviewed calcification on CT, T1 bright signal intensity, and cystic change on T2 weighted images for differentiating these two types. METHODS: We retrospectively reviewed the MRI and CT studies in 38 consecutive patients with pathologically proven craniopharyngiomas between January 2004 and February 2014 for the presence of calcification on CT scans, bright signal intensity on T1 weighted images, and cystic change on T2 weighted images. RESULTS: Of the 38 craniopharyngiomas, 30 were adamantinomatous type and 8 were papillary type. On CT scans, calcification was present in 25 of 38 tumors. All calcified tumors were adamantinomatous type. Twenty four of 38 tumors had bright signal intensity on T1 weighted images. Of these 24 tumors, 22 (91.7%) were adamantinomatous and 2 were papillary type. Cystic change on T2 weighted images was noted in 37 of 38 tumors; only 1 tumor with papillary type did not show cystic change. CONCLUSION: T1 bright signal intensity and calcification on CT scans uniformly favor the adamantinomatous type over papillary type of craniopharyngioma in children. However, these findings are more variable in adults where calcification and T1 bright signal intensity occur in 70.6% and 58.8% respectively of adult adamantinomatous types of craniopharyngiomas. |
format | Online Article Text |
id | pubmed-5028606 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | The Korean Neurosurgical Society |
record_format | MEDLINE/PubMed |
spelling | pubmed-50286062016-09-20 Craniopharyngiomas : Radiological Differentiation of Two Types Lee, In Ho Zan, Elcin Bell, W. Robert Burger, Peter C. Sung, Heejong Yousem, David M. J Korean Neurosurg Soc Clinical Article OBJECTIVE: To determine imaging features that may separate adamantinomatous and papillary variants of craniopharyngiomas given that tumors with adamantinomatous signature features are associated with higher recurrence rates, morbidity, and mortality. We specifically reviewed calcification on CT, T1 bright signal intensity, and cystic change on T2 weighted images for differentiating these two types. METHODS: We retrospectively reviewed the MRI and CT studies in 38 consecutive patients with pathologically proven craniopharyngiomas between January 2004 and February 2014 for the presence of calcification on CT scans, bright signal intensity on T1 weighted images, and cystic change on T2 weighted images. RESULTS: Of the 38 craniopharyngiomas, 30 were adamantinomatous type and 8 were papillary type. On CT scans, calcification was present in 25 of 38 tumors. All calcified tumors were adamantinomatous type. Twenty four of 38 tumors had bright signal intensity on T1 weighted images. Of these 24 tumors, 22 (91.7%) were adamantinomatous and 2 were papillary type. Cystic change on T2 weighted images was noted in 37 of 38 tumors; only 1 tumor with papillary type did not show cystic change. CONCLUSION: T1 bright signal intensity and calcification on CT scans uniformly favor the adamantinomatous type over papillary type of craniopharyngioma in children. However, these findings are more variable in adults where calcification and T1 bright signal intensity occur in 70.6% and 58.8% respectively of adult adamantinomatous types of craniopharyngiomas. The Korean Neurosurgical Society 2016-09 2016-09-08 /pmc/articles/PMC5028606/ /pubmed/27651864 http://dx.doi.org/10.3340/jkns.2016.59.5.466 Text en Copyright © 2016 The Korean Neurosurgical Society http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Clinical Article Lee, In Ho Zan, Elcin Bell, W. Robert Burger, Peter C. Sung, Heejong Yousem, David M. Craniopharyngiomas : Radiological Differentiation of Two Types |
title | Craniopharyngiomas : Radiological Differentiation of Two Types |
title_full | Craniopharyngiomas : Radiological Differentiation of Two Types |
title_fullStr | Craniopharyngiomas : Radiological Differentiation of Two Types |
title_full_unstemmed | Craniopharyngiomas : Radiological Differentiation of Two Types |
title_short | Craniopharyngiomas : Radiological Differentiation of Two Types |
title_sort | craniopharyngiomas : radiological differentiation of two types |
topic | Clinical Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5028606/ https://www.ncbi.nlm.nih.gov/pubmed/27651864 http://dx.doi.org/10.3340/jkns.2016.59.5.466 |
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