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Myelinating glia differentiation is regulated by extracellular matrix elasticity

The mechanical properties of living tissues have a significant impact on cell differentiation, but remain unexplored in the context of myelin formation and repair. In the PNS, the extracellular matrix (ECM) incorporates a basal lamina significantly denser than the loosely organized CNS matrix. Inhib...

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Detalles Bibliográficos
Autores principales: Urbanski, Mateusz M., Kingsbury, Lyle, Moussouros, Daniel, Kassim, Imran, Mehjabeen, Saraf, Paknejad, Navid, Melendez-Vasquez, Carmen V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5028715/
https://www.ncbi.nlm.nih.gov/pubmed/27646171
http://dx.doi.org/10.1038/srep33751