Cargando…

Exome Sequencing Reveals Primary Immunodeficiencies in Children with Community-Acquired Pseudomonas aeruginosa Sepsis

One out of three pediatric sepsis deaths in high income countries occur in previously healthy children. Primary immunodeficiencies (PIDs) have been postulated to underlie fulminant sepsis, but this concept remains to be confirmed in clinical practice. Pseudomonas aeruginosa (P. aeruginosa) is a comm...

Descripción completa

Detalles Bibliográficos
Autores principales:	Asgari, Samira, McLaren, Paul J., Peake, Jane, Wong, Melanie, Wong, Richard, Bartha, Istvan, Francis, Joshua R., Abarca, Katia, Gelderman, Kyra A., Agyeman, Philipp, Aebi, Christoph, Berger, Christoph, Fellay, Jacques, Schlapbach, Luregn J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2016
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5028722/ https://www.ncbi.nlm.nih.gov/pubmed/27703454 http://dx.doi.org/10.3389/fimmu.2016.00357

Ejemplares similares

Corrigendum: Exome Sequencing Reveals Primary Immunodeficiencies in Children with Community-Acquired Pseudomonas aeruginosa Sepsis
por: Asgari, Samira, et al.
Publicado: (2016)

Whole-exome Sequencing for the Identification of Rare Variants in Primary Immunodeficiency Genes in Children With Sepsis: A Prospective, Population-based Cohort Study
por: Borghesi, Alessandro, et al.
Publicado: (2020)

A39 Human exome sequencing to evaluate the impact of rare coding variation on HIV-1 control
por: McLaren, P.J., et al.
Publicado: (2017)

GuavaH: a compendium of host genomic data in HIV biology and disease
por: Bartha, István, et al.
Publicado: (2014)

Estimating the Respective Contributions of Human and Viral Genetic Variation to HIV Control
por: Bartha, István, et al.
Publicado: (2017)

Analysis of Stop-Gain and Frameshift Variants in Human Innate Immunity Genes
por: Rausell, Antonio, et al.
Publicado: (2014)

The Characteristics of Heterozygous Protein Truncating Variants in the Human Genome
por: Bartha, István, et al.
Publicado: (2015)

Copeptin concentration in cord blood in infants with early-onset sepsis, chorioamnionitis and perinatal asphyxia
por: Schlapbach, Luregn J, et al.
Publicado: (2011)

Estimating antibiotic coverage from linked microbiological and clinical data from the Swiss Paediatric Sepsis Study to support empiric antibiotic regimen selection
por: Cook, Aislinn, et al.
Publicado: (2023)

Adaptation on a genomic scale
por: Bartha, István, et al.
Publicado: (2015)

Sensitivity of ICD coding for sepsis in children—a population-based study
por: Endrich, Olga, et al.
Publicado: (2023)

HIV-1 and human genetic variation
por: McLaren, Paul J., et al.
Publicado: (2021)

Time-to-Positivity of Blood Cultures in Children With Sepsis
por: Dierig, Alexa, et al.
Publicado: (2018)

Prognostic accuracy of age-adapted SOFA, SIRS, PELOD-2, and qSOFA for in-hospital mortality among children with suspected infection admitted to the intensive care unit
por: Schlapbach, Luregn J., et al.
Publicado: (2017)

Contribution of Genetic Background and Clinical Risk Factors to Low-Trauma Fractures in Human Immunodeficiency Virus (HIV)-Positive Persons: The Swiss HIV Cohort Study
por: Junier, Thomas, et al.
Publicado: (2016)

Amino Acid Variation in HLA Class II Proteins Is a Major Determinant of Humoral Response to Common Viruses
por: Hammer, Christian, et al.
Publicado: (2015)

Paediatric patient stratification in the emergency department
por: Balamuth, Fran, et al.
Publicado: (2020)

Editorial: Sepsis in Neonates and Children
por: Giannoni, Eric, et al.
Publicado: (2020)

Correcting for Population Stratification Reduces False Positive and False Negative Results in Joint Analyses of Host and Pathogen Genomes
por: Naret, Olivier, et al.
Publicado: (2018)

Defining benefit threshold for extracorporeal membrane oxygenation in children with sepsis—a binational multicenter cohort study
por: Schlapbach, Luregn J., et al.
Publicado: (2019)

Mapping of positive selection sites in the HIV-1 genome in the context of RNA and protein structural constraints
por: Snoeck, Joke, et al.
Publicado: (2011)

Editorial: The Immunology of Sepsis—Understanding Host Susceptibility, Pathogenesis of Disease, and Avenues for Future Treatment
por: Schlapbach, Luregn J., et al.
Publicado: (2020)

The Role of Parental Concerns in the Recognition of Sepsis in Children: A Literature Review
por: Harley, Amanda, et al.
Publicado: (2019)

Exome Sequencing Diagnoses X-Linked Moesin-Associated Immunodeficiency in a Primary Immunodeficiency Case
por: Bradshaw, Gabrielle, et al.
Publicado: (2018)

Role of extracorporeal membrane oxygenation in children with sepsis: a systematic review and meta-analysis
por: Ramanathan, Kollengode, et al.
Publicado: (2020)

Prediction of recovery from multiple organ dysfunction syndrome in pediatric sepsis patients
por: Fan, Bowen, et al.
Publicado: (2022)

Paediatric sepsis: old wine in new bottles?
por: Schlapbach, Luregn J., et al.
Publicado: (2017)

Sepsis: Changing Definitions, Unchanging Treatment
por: Obonyo, Nchafatso Gikenyi, et al.
Publicado: (2019)

Corrigendum: Sepsis: Changing Definitions, Unchanging Treatment
por: Obonyo, Nchafatso Gikenyi, et al.
Publicado: (2020)

HLA Heterozygote Advantage against HIV-1 Is Driven by Quantitative and Qualitative Differences in HLA Allele-Specific Peptide Presentation
por: Arora, Jatin, et al.
Publicado: (2020)

Common Variable Immunodeficiency with Genetic Defects Identified by Whole Exome Sequencing
por: Li, Ran, et al.
Publicado: (2018)

Genetic Diagnosis Using Whole Exome Sequencing in Common Variable Immunodeficiency
por: Maffucci, Patrick, et al.
Publicado: (2016)

Differentiation in Quinolone Resistance by Virulence Genotype in Pseudomonas aeruginosa
por: Agnello, Melissa, et al.
Publicado: (2012)

Comprehensive Outline of Whole Exome Sequencing Data Analysis Tools Available in Clinical Oncology
por: Bartha, Áron, et al.
Publicado: (2019)

Multiancestry sex-stratified genomic associations with HIV viral load and controller status from the ICGH
por: Vergara, Candelaria, et al.
Publicado: (2023)

Recurrent Mycobacterium chelonae Skin Infection Unmasked as Factitious Disorder Using Bacterial Whole Genome Sequence Analysis
por: Flohr, Sarah, et al.
Publicado: (2020)

Parental and healthcare professional concern in the diagnosis of paediatric sepsis: a protocol for a prospective multicentre observational study
por: Sever, Zoe, et al.
Publicado: (2021)

A New Arthritis Therapy with Oxidative Burst Inducers
por: Hultqvist, Malin, et al.
Publicado: (2006)

Striking Decrease of Enteroviral Meningitis in Children During the COVID-19 Pandemic
por: Stoffel, Larissa, et al.
Publicado: (2021)

Exome sequencing of extreme phenotypes identifies DCTN4 as a modifier of chronic Pseudomonas aeruginosa infection in cystic fibrosis
por: Emond, Mary J, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_vpdh3sr3588qccg1inda5okntr