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Genetic Characterization of Plasmodium Putative Pantothenate Kinase Genes Reveals Their Essential Role in Malaria Parasite Transmission to the Mosquito

The metabolic machinery for the biosynthesis of Coenzyme A (CoA) from exogenous pantothenic acid (Vitamin B(5)) has long been considered as an excellent target for the development of selective antimicrobials. Earlier studies in the human malaria parasite Plasmodium falciparum have shown that pantoth...

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Detalles Bibliográficos
Autores principales: Hart, Robert J., Cornillot, Emmanuel, Abraham, Amanah, Molina, Emily, Nation, Catherine S., Ben Mamoun, Choukri, Aly, Ahmed S. I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5028760/
https://www.ncbi.nlm.nih.gov/pubmed/27644319
http://dx.doi.org/10.1038/srep33518