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Bcl-2 homologue Debcl enhances α-synuclein-induced phenotypes in Drosophila
BACKGROUND: Parkinson disease (PD) is a debilitating movement disorder that afflicts 1–2% of the population over 50 years of age. The common hallmark for both sporadic and familial forms of PD is mitochondrial dysfunction. Mammals have at least twenty proapoptotic and antiapoptotic Bcl-2 family memb...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
PeerJ Inc.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5028777/ https://www.ncbi.nlm.nih.gov/pubmed/27672511 http://dx.doi.org/10.7717/peerj.2461 |