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Prostate tumor attenuation in the nu/nu murine model due to anti-sarcosine antibodies in folate-targeted liposomes

Herein, we describe the preparation of liposomes with folate-targeting properties for the encapsulation of anti-sarcosine antibodies (antisarAbs@LIP) and sarcosine (sar@LIP). The competitive inhibitory effects of exogenously added folic acid supported the role of folate targeting in liposome interna...

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Detalles Bibliográficos
Autores principales: Heger, Zbynek, Polanska, Hana, Merlos Rodrigo, Miguel Angel, Guran, Roman, Kulich, Pavel, Kopel, Pavel, Masarik, Michal, Eckschlager, Tomas, Stiborova, Marie, Kizek, Rene, Adam, Vojtech
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5028781/
https://www.ncbi.nlm.nih.gov/pubmed/27646588
http://dx.doi.org/10.1038/srep33379