Cargando…

Hypermetabolism in B–lymphocytes from malignant hyperthermia susceptible individuals

Malignant hyperthermia (MH) is a pharmacogenetic disorder of skeletal muscle metabolism which is characterized by generalized muscle rigidity, increased body temperature, rhabdomyolysis, and severe metabolic acidosis. The underlying mechanism of MH involves excessive Ca(2+) release in myotubes via t...

Descripción completa

Detalles Bibliográficos
Autores principales: Hoppe, Kerstin, Hack, Guido, Lehmann–Horn, Frank, Jurkat–Rott, Karin, Wearing, Scott, Zullo, Alberto, Carsana, Antonella, Klingler, Werner
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5028841/
https://www.ncbi.nlm.nih.gov/pubmed/27646467
http://dx.doi.org/10.1038/srep33372