Cargando…

Hypermetabolism in B–lymphocytes from malignant hyperthermia susceptible individuals

Malignant hyperthermia (MH) is a pharmacogenetic disorder of skeletal muscle metabolism which is characterized by generalized muscle rigidity, increased body temperature, rhabdomyolysis, and severe metabolic acidosis. The underlying mechanism of MH involves excessive Ca(2+) release in myotubes via t...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hoppe, Kerstin, Hack, Guido, Lehmann–Horn, Frank, Jurkat–Rott, Karin, Wearing, Scott, Zullo, Alberto, Carsana, Antonella, Klingler, Werner
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5028841/ https://www.ncbi.nlm.nih.gov/pubmed/27646467 http://dx.doi.org/10.1038/srep33372

Ejemplares similares

Paxilline Prevents the Onset of Myotonic Stiffness in Pharmacologically Induced Myotonia: A Preclinical Investigation
por: Hoppe, Kerstin, et al.
Publicado: (2020)

Relevance of pathogenicity prediction tools in human RYR1 variants of unknown significance
por: Hoppe, Kerstin, et al.
Publicado: (2021)

Functional and genetic characterization of clinical malignant hyperthermia crises: a multi-centre study
por: Klingler, Werner, et al.
Publicado: (2014)

Exercise-Induced Rhabdomyolysis and Stress-Induced Malignant Hyperthermia Events, Association with Malignant Hyperthermia Susceptibility, and RYR1 Gene Sequence Variations
por: Carsana, Antonella
Publicado: (2013)

The role of fibrosis in Duchenne muscular dystrophy
por: KLINGLER, WERNER, et al.
Publicado: (2012)

Voltage modulates halothane-triggered Ca(2+) release in malignant hyperthermia-susceptible muscle
por: Zullo, Alberto, et al.
Publicado: (2018)

Structural and Functional Changes in the Coupling of Fascial Tissue, Skeletal Muscle, and Nerves During Aging
por: Zullo, Alberto, et al.
Publicado: (2020)

Do Hyperpolarization-induced Proton Currents Contribute to the Pathogenesis of Hypokalemic Periodic Paralysis, a Voltage Sensor Channelopathy?
por: Jurkat-Rott, Karin, et al.
Publicado: (2007)

Pathophysiological Role of Omega Pore Current in Channelopathies
por: Jurkat-Rott, Karin, et al.
Publicado: (2012)

Rare KCNJ18 variants do not explain hypokalaemic periodic paralysis in 263 unrelated patients
por: Kuhn, Marius, et al.
Publicado: (2016)

Eplerenone repolarizes muscle membrane through Na,K-ATPase activation by Tyr10 dephosphorylation
por: Breitenbach, Simon, et al.
Publicado: (2016)

The impact of permanent muscle weakness on quality of life in periodic paralysis: a survey of 66 patients
por: CAVEL-GREANT, DEBORAH, et al.
Publicado: (2012)

Domain III S4 in closed-state fast inactivation: Insights from a periodic paralysis mutation
por: Groome, James R, et al.
Publicado: (2014)

State of the art in hereditary muscle channelopathies
por: Jurkat-Rott, K., et al.
Publicado: (2010)

Sodium channelopathies of skeletal muscle result from gain or loss of function
por: Jurkat-Rott, Karin, et al.
Publicado: (2010)

Successful treatment of periodic paralysis with coenzyme Q10: two case reports
por: Da, Yuwei, et al.
Publicado: (2016)

Kir2.2 p.Thr140Met: a genetic susceptibility to sporadic periodic paralysis
por: FAN, CHUNXIANG, et al.
Publicado: (2018)

A gating model for wildtype and R1448H Nav1.4 channels in paramyotonia
por: HOLZHERR, BORIS, et al.
Publicado: (2014)

A novel N440K sodium channel mutation causes myotonia with exercise-induced weakness - exclusion of CLCN1 exon deletion/duplication by MLPA
por: Lehmann-Horn, F., et al.
Publicado: (2011)

Effects of Theophylline on Anesthetized Malignant Hyperthermia-Susceptible Pigs
por: Fiege, Marko, et al.
Publicado: (2011)

I-10 Pathogenesis of muscle degeneration in periodic paralyses and DMD
por: Lehmann-Horn, F., et al.
Publicado: (2011)

Fascial tissue research in sports medicine: from molecules to tissue adaptation, injury and diagnostics: consensus statement
por: Zügel, Martina, et al.
Publicado: (2018)

Characterization of hyperkalemic periodic paralysis: a survey of genetically diagnosed individuals
por: Charles, G., et al.
Publicado: (2013)

Na(V)1.4 DI-S4 periodic paralysis mutation R222W enhances inactivation and promotes leak current to attenuate action potentials and depolarize muscle fibers
por: Bayless-Edwards, Landon, et al.
Publicado: (2018)

Na(V)1.4 mutations cause hypokalaemic periodic paralysis by disrupting IIIS4 movement during recovery
por: Groome, James R., et al.
Publicado: (2014)

Rationale for treating oedema in Duchenne muscular dystrophy with eplerenone
por: LEHMANN-HORN, FRANK, et al.
Publicado: (2012)

The effect of succinylcholine on malignant hyperthermia events in susceptible swine
por: Schuster, Frank, et al.
Publicado: (2014)

Anesthesia for muscle biopsy to test susceptibility to malignant hyperthermia
por: Silva, Helga Cristina Almeida da, et al.
Publicado: (2019)

Transient compartment-like syndrome and normokalaemic periodic paralysis due to a Ca(v)1.1 mutation
por: Fan, Chunxiang, et al.
Publicado: (2013)

In vitro effects of levosimendan on muscle of malignant hyperthermia susceptible and non-susceptible swine
por: Schuster, Frank, et al.
Publicado: (2018)

Erythrocyte osmotic response test on malignant hyperthermia-susceptible pigs
por: King, WA, et al.
Publicado: (1976)

What is “Hyper” in the ALS Hypermetabolism?
por: Ferri, Alberto, et al.
Publicado: (2017)

Hypermetabolic pseudotumour of the chest wall
por: Kamal, Yasser Ali, et al.
Publicado: (2020)

Early-onset familial hemiplegic migraine due to a novel SCN1A mutation
por: Fan, Chunxiang, et al.
Publicado: (2016)

Malignant hyperthermia
por: Rosenberg, Henry, et al.
Publicado: (2007)

Malignant hyperthermia
por: Kim, Dong-Chan
Publicado: (2012)

Functional in vitro tension measurements of fascial tissue – a novel modified superfusion approach
por: Schleip, R., et al.
Publicado: (2016)

Is There a Link between Exertional Heat Stroke and Susceptibility to Malignant Hyperthermia?
por: Sagui, Emmanuel, et al.
Publicado: (2015)

Congenital hypermetabolism and uncoupled oxidative phosphorylation
por: Ganetzky, Rebecca D., et al.
Publicado: (2022)

Modulation of Burn Hypermetabolism in Preclinical Models
por: Eldaly, Abdullah S, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_2gkvcpnj2avmk5h37qpku01tr4