Cargando…
Hypermetabolism in B–lymphocytes from malignant hyperthermia susceptible individuals
Malignant hyperthermia (MH) is a pharmacogenetic disorder of skeletal muscle metabolism which is characterized by generalized muscle rigidity, increased body temperature, rhabdomyolysis, and severe metabolic acidosis. The underlying mechanism of MH involves excessive Ca(2+) release in myotubes via t...
Autores principales: | Hoppe, Kerstin, Hack, Guido, Lehmann–Horn, Frank, Jurkat–Rott, Karin, Wearing, Scott, Zullo, Alberto, Carsana, Antonella, Klingler, Werner |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5028841/ https://www.ncbi.nlm.nih.gov/pubmed/27646467 http://dx.doi.org/10.1038/srep33372 |
Ejemplares similares
-
Paxilline Prevents the Onset of Myotonic Stiffness in Pharmacologically Induced Myotonia: A Preclinical Investigation
por: Hoppe, Kerstin, et al.
Publicado: (2020) -
Relevance of pathogenicity prediction tools in human RYR1 variants of unknown significance
por: Hoppe, Kerstin, et al.
Publicado: (2021) -
Functional and genetic characterization of clinical malignant hyperthermia crises: a multi-centre study
por: Klingler, Werner, et al.
Publicado: (2014) -
Exercise-Induced Rhabdomyolysis and Stress-Induced Malignant Hyperthermia Events, Association with Malignant Hyperthermia Susceptibility, and RYR1 Gene Sequence Variations
por: Carsana, Antonella
Publicado: (2013) -
The role of fibrosis
in Duchenne muscular dystrophy
por: KLINGLER, WERNER, et al.
Publicado: (2012)