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Identification of the Metabolic Enzyme Involved Morusin Metabolism and Characterization of Its Metabolites by Ultraperformance Liquid Chromatography Quadrupole Time-of-Flight Mass Spectrometry (UPLC/Q-TOF-MS/MS)

Morusin, the important active component of a traditional Chinese medicine, Morus alba L., has been shown to exhibit many vital pharmacological activities. In this study, six recombinant CYP450 supersomes and liver microsomes were used to perform metabolic studies. Chemical inhibition studies and scr...

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Detalles Bibliográficos
Autores principales:	Shi, Xianbao, Mackie, Brianna, Zhang, Gang, Yang, Shuman, Song, Yonggui, Su, Dan, Liu, Yali, Shan, Lina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5028857/ https://www.ncbi.nlm.nih.gov/pubmed/27698677 http://dx.doi.org/10.1155/2016/9240103

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