Advanced glycation end products increase lipids accumulation in macrophages through upregulation of receptor of advanced glycation end products: increasing uptake, esterification and decreasing efflux of cholesterol

BACKGROUND: Previous reports have suggested that advanced glycation end products (AGEs) participate in the pathogenesis of diabetic macroangiopathy. Our previous study have found that AGEs can increase the lipid droplets accumulation in aortas of diabetic rats, but the current understanding of the m...

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Detalles Bibliográficos
Autores principales: Xu, Lei, Wang, Yi-Ru, Li, Pei-Cheng, Feng, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5028926/
https://www.ncbi.nlm.nih.gov/pubmed/27644038
http://dx.doi.org/10.1186/s12944-016-0334-0

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