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Repeated cycles of 5-fluorouracil chemotherapy impaired anti-tumor functions of cytotoxic T cells in a CT26 tumor-bearing mouse model

BACKGROUND: Recently, the immunostimulatory roles of chemotherapeutics have been increasingly revealed, although bone marrow suppression is still a common toxicity of chemotherapy. While the numbers and ratios of different immune subpopulations are analyzed after chemotherapy, changes to immune stat...

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Detalles Bibliográficos
Autores principales: Wu, Yanhong, Deng, Zhenling, Wang, Huiru, Ma, Wenbo, Zhou, Chunxia, Zhang, Shuren
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5028929/
https://www.ncbi.nlm.nih.gov/pubmed/27645787
http://dx.doi.org/10.1186/s12865-016-0167-7