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Repeated cycles of 5-fluorouracil chemotherapy impaired anti-tumor functions of cytotoxic T cells in a CT26 tumor-bearing mouse model

BACKGROUND: Recently, the immunostimulatory roles of chemotherapeutics have been increasingly revealed, although bone marrow suppression is still a common toxicity of chemotherapy. While the numbers and ratios of different immune subpopulations are analyzed after chemotherapy, changes to immune stat...

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Detalles Bibliográficos
Autores principales:	Wu, Yanhong, Deng, Zhenling, Wang, Huiru, Ma, Wenbo, Zhou, Chunxia, Zhang, Shuren
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5028929/ https://www.ncbi.nlm.nih.gov/pubmed/27645787 http://dx.doi.org/10.1186/s12865-016-0167-7

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