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Neonatal monocytes exhibit a unique histone modification landscape
BACKGROUND: Neonates have dampened expression of pro-inflammatory cytokines and difficulty clearing pathogens. This makes them uniquely susceptible to infections, but the factors regulating neonatal-specific immune responses are poorly understood. Epigenetics, including histone modifications, can ac...
Autores principales: | Bermick, Jennifer R., Lambrecht, Nathalie J., denDekker, Aaron D., Kunkel, Steven L., Lukacs, Nicholas W., Hogaboam, Cory M., Schaller, Matthew A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5028999/ https://www.ncbi.nlm.nih.gov/pubmed/27660665 http://dx.doi.org/10.1186/s13148-016-0265-7 |
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