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Growth differentiation factor 15 contributes to cancer-associated fibroblasts-mediated chemo-protection of AML cells

BACKGROUND: Chemo-resistance is still a major obstacle in efforts to overcome acute myeloid leukemia (AML). An emerging concept has proposed that interactions between the bone marrow (BM) microenvironment and leukemia cells reduce the sensitivity of the leukemia cells to chemotherapy. As an importan...

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Detalles Bibliográficos
Autores principales:	Zhai, Yuanmei, Zhang, Jing, Wang, Hui, Lu, Wei, Liu, Sihong, Yu, Yehua, Weng, Wei, Ding, Zhiyong, Zhu, Qi, Shi, Jun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5029001/ https://www.ncbi.nlm.nih.gov/pubmed/27643489 http://dx.doi.org/10.1186/s13046-016-0405-0

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