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Bmi-1 regulates stem cell-like properties of gastric cancer cells via modulating miRNAs

BACKGROUND: B cell-specific Moloney murine leukemia virus integration site 1 (Bmi-1) plays an important role in regulating stemness in some kinds of cancer. However, the mechanisms remain unclear. This study was to investigate whether and how Bmi-1 regulates stemness of gastric cancer. METHODS: We f...

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Detalles Bibliográficos
Autores principales: Wang, Xiaofeng, Wang, Chang, Zhang, Xiaowei, Hua, Ruixi, Gan, Lu, Huang, Mingzhu, Zhao, Liqin, Ni, Sujie, Guo, Weijian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5029045/
https://www.ncbi.nlm.nih.gov/pubmed/27644439
http://dx.doi.org/10.1186/s13045-016-0323-9